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Methyl-directed repair of DNA base-pair mismatches in vitro.

An assay has been developed that permits analysis of DNA mismatch repair in cell-free extracts of Escherichia coli. The method relies on repair of heteroduplex molecules of f1 R229 DNA, which contain a base-pair mismatch within the single EcoRI site of the molecule. As observed with mismatch heterod...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lu, A L, Clark, S, Modrich, P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384099/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6308634/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.15.4639
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