Methyl-directed repair of DNA base-pair mismatches in vitro.

An assay has been developed that permits analysis of DNA mismatch repair in cell-free extracts of Escherichia coli. The method relies on repair of heteroduplex molecules of f1 R229 DNA, which contain a base-pair mismatch within the single EcoRI site of the molecule. As observed with mismatch heterod...

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Bibliographische Detailangaben
Hauptverfasser: Lu, A L, Clark, S, Modrich, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1983
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC384099/
https://ncbi.nlm.nih.gov/pubmed/6308634
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