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Polyamines are traps for reactive intermediates in furan metabolism

Furan is toxic and carcinogenic in rodents. Because of the large potential for human exposure, furan is classified as a possible human carcinogen. The detailed mechanism by which furan causes toxicity and cancer is not yet known. Since furan toxicity requires cytochrome P450-catalyzed oxidation of f...

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Bibliographic Details
Main Authors: Peterson, Lisa A., Phillips, Martin B., Lu, Ding, Sullivan, Mathilde M.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221807/
https://ncbi.nlm.nih.gov/pubmed/21842885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200273z
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