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Degraded protein adducts of cis-2-butene-1,4-dial are urinary and hepatocyte metabolites of furan
Furan is a liver toxicant and carcinogen in rodents. Based on these observations and the large potential for human exposure, furan has been classified as a possible human carcinogen. The mechanism of tumor induction by furan is unknown. However, the toxicity requires cytochrome P450 catalyzed oxidat...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696637/ https://ncbi.nlm.nih.gov/pubmed/19441776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800377v |
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