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Comparative Metabolism of Furan in Rodent and Human Cryopreserved Hepatocytes

Furan is a liver toxicant and carcinogen in rodents. Although humans are most likely exposed to furan through a variety of sources, the effect of furan exposure on human health is still unknown. In rodents, furan requires metabolism to exert its toxic effects. The initial product of the cytochrome P...

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Bibliografiske detaljer
Main Authors: Gates, Leah A., Phillips, Martin B., Matter, Brock A., Peterson, Lisa A.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053996/
https://ncbi.nlm.nih.gov/pubmed/24751574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.057794
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