A carregar...
Covalent Modification of Cytochrome C by Reactive Metabolites of Furan
Metabolism of the hepatotoxicant furan leads to protein adduct formation in the target organ. The initial bioactivation step involves cytochrome P450-catalyzed oxidation of furan, generating cis-2-butene-1,4-dial (BDA). BDA reacts with lysine to form pyrrolin-2-one adducts. Metabolic studies indicat...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908668/ https://ncbi.nlm.nih.gov/pubmed/24364757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400368r |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|