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Reactive Metabolites in the Biotransformation of Molecules Containing a Furan Ring
Many xenobiotics containing a furan ring are toxic and/or carcinogenic. The harmful effects of these compounds require furan ring oxidation. This reaction generates an electrophilic intermediate. Depending on the furan ring substituents, the intermediate is either an epoxide or a cis-enedione with m...
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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2012
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3574180/ https://ncbi.nlm.nih.gov/pubmed/23061605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3003824 |
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