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Hdm2- and proteasome-dependent turnover limits p21 accumulation during S phase

Double-strand DNA breaks detected in different phases of the cell cycle induce molecularly distinct checkpoints downstream of the ATM kinase. p53 is known to induce arrest of cells in G(1) and occasionally G(2) phase but not S phase following ionizing radiation, a time at which the MRN complex and c...

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Detalhes bibliográficos
Main Authors: Ciznadija, Daniel, Zhu, Xin-Hua, Koff, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219540/
https://ncbi.nlm.nih.gov/pubmed/21768776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.16.16725
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