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Hdm2- and proteasome-dependent turnover limits p21 accumulation during S phase
Double-strand DNA breaks detected in different phases of the cell cycle induce molecularly distinct checkpoints downstream of the ATM kinase. p53 is known to induce arrest of cells in G(1) and occasionally G(2) phase but not S phase following ionizing radiation, a time at which the MRN complex and c...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219540/ https://ncbi.nlm.nih.gov/pubmed/21768776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.16.16725 |
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