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Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart

BACKGROUND AND OBJECTIVE: Cardiac-directed adenylyl cyclase 6 (AC6) expression attenuates left ventricular (LV) hypertrophy and dysfunction in cardiomyopathy, but its effects in the pressure-overloaded heart are unknown. METHODS: Mice with cardiac-directed and regulated expression of AC6 underwent t...

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Detalhes bibliográficos
Main Authors: Sugano, Yasuo, Lai, N. Chin, Gao, Mei Hua, Firth, Amy L., Yuan, Jason X.-J., Lew, Wilbur Y.W., Hammond, H. Kirk
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219303/
https://ncbi.nlm.nih.gov/pubmed/21195051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.12.113
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