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Adenylyl Cyclase 6 Deletion Reduces Left Ventricular Hypertrophy, Dilation, Dysfunction, and Fibrosis in Pressure-Overloaded Female Mice
OBJECTIVES: This study sought to test the hypothesis that pressure stress of the adenylyl cyclase 6-deleted (AC6-KO) heart would result in excessive hypertrophy, early dilation and dysfunction, and increased fibrosis. BACKGROUND: Cardiac-directed AC6 expression attenuates left ventricular (LV) hyper...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081694/ https://ncbi.nlm.nih.gov/pubmed/20359598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2009.11.066 |
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