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Adenylyl Cyclase 6 Deletion Reduces Left Ventricular Hypertrophy, Dilation, Dysfunction, and Fibrosis in Pressure-Overloaded Female Mice

OBJECTIVES: This study sought to test the hypothesis that pressure stress of the adenylyl cyclase 6-deleted (AC6-KO) heart would result in excessive hypertrophy, early dilation and dysfunction, and increased fibrosis. BACKGROUND: Cardiac-directed AC6 expression attenuates left ventricular (LV) hyper...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tang, Tong, Lai, N. Chin, Hammond, H. Kirk, Roth, David M., Yang, Yuan, Guo, Tracy, Gao, Mei Hua
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081694/
https://ncbi.nlm.nih.gov/pubmed/20359598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2009.11.066
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