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Adenylyl Cyclase 6 Improves Calcium Uptake and LV Function in Aged Hearts
OBJECTIVES: This study sought to test the hypothesis that activation of adenylyl cyclase 6 (AC6) expression in cardiac myocytes improves Ca(2+) uptake and LV function in aging mice. BACKGROUND: Aging hearts exhibit impaired β-adrenergic receptor signaling and left ventricular (LV) dysfunction. METHO...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3087976/ https://ncbi.nlm.nih.gov/pubmed/21527160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2010.11.052 |
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