Hexose-6-Phosphate Dehydrogenase Contributes to Skeletal Muscle Homeostasis Independent of 11β-Hydroxysteroid Dehydrogenase Type 1

Glucose-6-phosphate (G6P) metabolism by the enzyme hexose-6-phosphate dehydrogenase (H6PDH) within the sarcoplasmic reticulum lumen generates nicotinamide adenine dinucleotide phosphate (reduced) to provide the redox potential for the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) to acti...

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Detalhes bibliográficos
Main Authors: Semjonous, Nina M., Sherlock, Mark, Jeyasuria, Pancharatnam, Parker, Keith L., Walker, Elizabeth A., Stewart, Paul M., Lavery, Gareth G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219053/
https://ncbi.nlm.nih.gov/pubmed/21106871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0957
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