Direct regulation of glucose and not insulin on hepatic hexose-6-phosphate dehydrogenase and 11β-hydroxysteroid dehydrogenase type 1

Abnormal hepatic gluconeogenesis contributes significantly to both fasting and non-fasting hyperglycemia of patients with type 2 diabetes. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) regulates the key hepatic gluconeogenic enzymes including phosphoenolpyruvate carboxykinase (PEPCK) and glucos...

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Hlavní autoři: Fan, Zheng, Du, Hongwei, Zhang, Ming, Meng, Zhaojie, Chen, Li, Liu, Yanjun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741409/
https://ncbi.nlm.nih.gov/pubmed/21163329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2010.12.010
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