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Specific Reduction of Glucose-6-Phosphate Transporter May Contribute to Down-regulation of Hepatic 11β-hydroxysteroid Dehydrogenase Type 1 in Diabetic Mice
Pre-receptor activation of glucocorticoids via 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) has been identified as an important mediator of the metabolic syndrome. Hexose-6-phosphate dehydrogenase (H6PDH) mediates 11β-HSD1 amplifying tissue glucocorticoid production by driving intracellular NA...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763023/ https://ncbi.nlm.nih.gov/pubmed/23267038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-12-0223 |
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