Lack of Significant Metabolic Abnormalities in Mice with Liver-Specific Disruption of 11β-Hydroxysteroid Dehydrogenase Type 1

Glucocorticoids (GC) are implicated in the development of metabolic syndrome, and patients with GC excess share many clinical features, such as central obesity and glucose intolerance. In patients with obesity or type 2 diabetes, systemic GC concentrations seem to be invariably normal. Tissue GC con...

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Bibliografiske detaljer
Main Authors: Lavery, Gareth G., Zielinska, Agnieszka E., Gathercole, Laura L., Hughes, Beverly, Semjonous, Nina, Guest, Phillip, Saqib, Khalid, Sherlock, Mark, Reynolds, Gary, Morgan, Stuart A., Tomlinson, Jeremy W., Walker, Elizabeth A., Rabbitt, Elizabeth H., Stewart, Paul M.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2012
Fag:
Glucocorticoids-CRH-ACTH-Adrenal
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475725/
https://ncbi.nlm.nih.gov/pubmed/22555437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1019
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