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SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells

Emerging evidence suggests that Sirtuin 6 (SIRT6) functions as a longevity assurance gene by promoting genomic stability, regulating metabolic processes and attenuating inflammation. Here, we examine the effect of SIRT6 activation on cancer cells. We show that SIRT6 overexpression induces massive ap...

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Detalhes bibliográficos
Main Authors: Van Meter, Michael, Mao, Zhiyong, Gorbunova, Vera, Seluanov, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218623/
https://ncbi.nlm.nih.gov/pubmed/21900744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.18.17435
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