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SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells

Emerging evidence suggests that Sirtuin 6 (SIRT6) functions as a longevity assurance gene by promoting genomic stability, regulating metabolic processes and attenuating inflammation. Here, we examine the effect of SIRT6 activation on cancer cells. We show that SIRT6 overexpression induces massive ap...

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書目詳細資料
Main Authors: Van Meter, Michael, Mao, Zhiyong, Gorbunova, Vera, Seluanov, Andrei
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218623/
https://ncbi.nlm.nih.gov/pubmed/21900744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.18.17435
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