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SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells

Emerging evidence suggests that Sirtuin 6 (SIRT6) functions as a longevity assurance gene by promoting genomic stability, regulating metabolic processes and attenuating inflammation. Here, we examine the effect of SIRT6 activation on cancer cells. We show that SIRT6 overexpression induces massive ap...

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Bibliografische gegevens
Hoofdauteurs: Van Meter, Michael, Mao, Zhiyong, Gorbunova, Vera, Seluanov, Andrei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218623/
https://ncbi.nlm.nih.gov/pubmed/21900744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.18.17435
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