A carregar...
SIRT6 promotes DNA repair under stress by activating PARP1
SIRT6 is a mammalian homolog of the yeast Sir2 deacetylase that promotes longevity in yeast and invertebrates. Mice deficient for SIRT6 exhibit premature aging and genome instability. Here we show that in mammalian cells subjected to oxidative stress SIRT6 is recruited to the sites of DNA double-str...
Na minha lista:
| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5472447/ https://ncbi.nlm.nih.gov/pubmed/21680843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1202723 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|