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Distinct requirements of hematopoietic stem cell activity and Nras G12D signaling in different cell types during leukemogenesis
We previously showed that widespread expression of Nras G12D/G12D from its endogenous locus in mice leads to an acute myeloproliferative disease (MPD) with a complete penetrance, whereas bone marrow-specific expression of Nras G12D/G12D in recipient mice did not result in sustained MPD phenotypes bu...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218596/ https://ncbi.nlm.nih.gov/pubmed/21857161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.17.17195 |
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