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Interaction of the ARF tumor suppressor with cytosolic HSP70 contributes to its autophagy function

The p14/p19(ARF) (ARF) tumor suppressor gene is frequently mutated in human cancer. Recently ARF has been shown to localize to mitochondria and to induce autophagy. However the controls that regulate the trafficking of ARF to mitochondria remain unknown. We recently reported that 2-phenylethynesulfo...

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Hlavní autoři: Pimkina, Julia S, Murphy, Maureen E
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218591/
https://ncbi.nlm.nih.gov/pubmed/21738007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.6.15976
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