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A conserved domain in exon 2 coding for the human and murine ARF tumor suppressor protein is required for autophagy induction
The ARF tumor suppressor, encoded by the CDKN2A gene, has a well-defined role regulating TP53 stability; this activity maps to exon 1β of CDKN2A. In contrast, little is known about the function(s) of exon 2 of ARF, which contains the majority of mutations in human cancer. In addition to controlling...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Autophagy |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623555/ https://ncbi.nlm.nih.gov/pubmed/23939042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.25831 |
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