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ARF, autophagy and tumor suppression

Autophagy plays a critical role in the initiation and progression of tumors. The exact nature of this role, however, is complex. Autophagy is suppressive to tumor initiation, and reduces genomic instability. Genes with key roles in autophagy are mutated in human cancer, and knock-out mice for certai...

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Bibliografske podrobnosti
Main Authors: Pimkina, Julia, Murphy, Maureen E.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667648/
https://ncbi.nlm.nih.gov/pubmed/19221462
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