Nalaganje...

The spliceosome as an indicted conspirator in myeloid malignancies

Data from two recent studies of whole-exome sequencing of myelodysplastic syndrome (MDS) suggests spliceosome mutations have clinical relevance. Identifying the impact of these mutations on pre-mRNA splicing and MDS pathogenesis holds promise for targeted modulation of mRNA splicing in MDS.

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Abdel-Wahab, Omar, Levine, Ross
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218079/
https://ncbi.nlm.nih.gov/pubmed/22014568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.10.004
Oznake: Označite
Brez oznak, prvi označite!