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Mutations in spliceosome genes and therapeutic opportunities in myeloid malignancies
Since the discovery of RNA splicing more than 40 years ago, our comprehension of the molecular events orchestrating constitutive and alternative splicing has greatly improved. Dysregulation of pre‐mRNA splicing has been observed in many human diseases including neurodegenerative diseases and cancer....
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| Publicado en: | Genes Chromosomes Cancer |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley & Sons, Inc.
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6852509/ https://ncbi.nlm.nih.gov/pubmed/31334570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22784 |
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