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Mutations in spliceosome genes and therapeutic opportunities in myeloid malignancies

Since the discovery of RNA splicing more than 40 years ago, our comprehension of the molecular events orchestrating constitutive and alternative splicing has greatly improved. Dysregulation of pre‐mRNA splicing has been observed in many human diseases including neurodegenerative diseases and cancer....

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Detalhes bibliográficos
Publicado no:Genes Chromosomes Cancer
Main Authors: Taylor, Justin, Lee, Stanley C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852509/
https://ncbi.nlm.nih.gov/pubmed/31334570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22784
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