Yüklüyor......
Identification of endogenous ligands bound to bacterially expressed human and E. coli dihydrofolate reductase by 2D NMR
Dihydrofolate reductase (DHFR) is a well-studied drug target and a paradigm for understanding enzyme catalysis. Preparation of pure DHFR samples, in defined ligand-bound states, is a prerequisite for in vitro studies and drug discovery efforts. We use NMR spectroscopy to monitor ligand content of hu...
Kaydedildi:
| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3215841/ https://ncbi.nlm.nih.gov/pubmed/22024482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.10.014 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|