PBP 2a Mutations Producing Very-High-Level Resistance to Beta-Lactams

Resistance to the beta-lactam class of antibiotics in methicillin-resistant Staphylococcus aureus (MRSA) is mediated by PBP 2a, a synthetic bacterial cell wall penicillin-binding protein with a low affinity of binding to beta-lactams that is encoded by mecA. Beta-lactams that bind to PBP 2a with a h...

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Bibliografiska uppgifter
Huvudupphovsmän: Katayama, Yuki, Zhang, Hong-Zhong, Chambers, Henry F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC321522/
https://ncbi.nlm.nih.gov/pubmed/14742194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.453-459.2004
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