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PBP 2a Mutations Producing Very-High-Level Resistance to Beta-Lactams
Resistance to the beta-lactam class of antibiotics in methicillin-resistant Staphylococcus aureus (MRSA) is mediated by PBP 2a, a synthetic bacterial cell wall penicillin-binding protein with a low affinity of binding to beta-lactams that is encoded by mecA. Beta-lactams that bind to PBP 2a with a h...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC321522/ https://ncbi.nlm.nih.gov/pubmed/14742194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.453-459.2004 |
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