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TDP-43-Based Animal Models of Neurodegeneration: New Insights into ALS Pathology and Pathophysiology

The clinical and pathological overlap between amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) suggests these diseases share common underlying mechanisms, a suggestion underscored by the discovery that TDP-43 inclusions are a key pathologic feature in both ALS and FTL...

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Autors principals: Wegorzewska, Iga, Baloh, Robert H.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214943/
https://ncbi.nlm.nih.gov/pubmed/21124004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321547
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