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TDP-43: The relationship between protein aggregation and neurodegeneration in ALS and FTLD

Accumulations of aggregated proteins are a key feature of the pathology of all of the major neurodegenerative diseases. Amyotrophic lateral sclerosis (ALS) was brought into this fold quite recently, with the discovery of TDP-43 inclusions in nearly all ALS cases. In part this discovery was fueled by...

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Hlavní autor: Baloh, Robert H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177991/
https://ncbi.nlm.nih.gov/pubmed/21777387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2011.08256.x
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