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Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD–ALS spectrum disorders

Aggregation of misfolded TAR DNA-binding protein 43 (TDP-43) is a striking hallmark of neurodegenerative processes that are observed in several neurological disorders, and in particular in most patients diagnosed with frontotemporal lobar degeneration (FTLD) or amyotrophic lateral sclerosis (ALS). A...

詳細記述

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書誌詳細
主要な著者: Janssens, Jonathan, Van Broeckhoven, Christine
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782069/
https://ncbi.nlm.nih.gov/pubmed/23900071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt349
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