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Molecular Mechanisms Underlying TDP-43 Pathology in Cellular and Animal Models of ALS and FTLD

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are neurodegenerative disorders that exist on a disease spectrum due to pathological, clinical and genetic overlap. In up to 97% of ALS cases and ~50% of FTLD cases, the primary pathological protein observed in affected...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wood, Alistair, Gurfinkel, Yuval, Polain, Nicole, Lamont, Wesley, Lyn Rea, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125728/
https://ncbi.nlm.nih.gov/pubmed/33946763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094705
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