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Transforming Growth Factor β/Smad3 Signaling Regulates IRF-7 Function and Transcriptional Activation of the Beta Interferon Promoter
The rapid induction of alpha interferon (IFN-α) and IFN-β expression plays a critical role in the innate immune response against viral infection. We studied the effects of transforming growth factor β (TGF-β) and its intracellular effectors, the Smads, on the function of IRF-7, an essential transcri...
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| Опубликовано в: : | Mol Cell Biol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14729983/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.3.1411-1425.2004 |
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