Bridging the Gap between Preclinical and Clinical Microbicide Trials: Blind Evaluation of Candidate Gels in Murine Models of Efficacy and Safety

BACKGROUND: Despite significant protection in preclinical studies, cellulose sulfate (CS) failed to protect women against HIV-1/2 and was associated with a trend toward increased HIV-1 acquisition in one of the clinical trials. These results highlight the need for preclinical tests more predictive o...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Segarra, Theodore J., Fakioglu, Esra, Cheshenko, Natalia, Wilson, Sarah S., Mesquita, Pedro M. M., Doncel, Gustavo F., Herold, Betsy C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214080/
https://ncbi.nlm.nih.gov/pubmed/22096611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027675
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller