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Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching
BACKGROUND: Antisense oligomer induced exon skipping aims to reduce the severity of Duchenne muscular dystrophy by redirecting splicing during pre-RNA processing such that the causative mutation is by-passed and a shorter but partially functional Becker muscular dystrophy-like dystrophin isoform is...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3213239/ https://ncbi.nlm.nih.gov/pubmed/22013876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-141 |
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