Biophysical Analysis of the Binding of WW Domains of YAP2 Transcriptional Regulator to PPXY Motifs within WBP1 and WBP2 Adaptors

YAP2 transcriptional regulator mediates a plethora of cellular functions, including the newly discovered Hippo tumor suppressor pathway, by virtue of its ability to recognize WBP1 and WBP2 signaling adaptors among a wide variety of other ligands. Herein, using isothermal titration calorimery (ITC) a...

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Autori principali: McDonald, Caleb B., McIntosh, Samantha K. N., Mikles, David C., Bhat, Vikas, Deegan, Brian J., Seldeen, Kenneth L., Saeed, Ali M., Buffa, Laura, Sudol, Marius, Nawaz, Zafar, Farooq, Amjad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210484/
https://ncbi.nlm.nih.gov/pubmed/21981024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201286p
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