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Biophysical Basis of the Binding of WWOX Tumor Suppressor to WBP1 and WBP2 Adaptors

The WWOX tumor suppressor participates in a diverse array of cellular activities by virtue of its ability to recognize WBP1 and WBP2 signaling adaptors among a wide variety of other ligands. Herein, using a multitude of biophysical techniques, we provide evidence that while the WW1 domain of WWOX bi...

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Detalhes bibliográficos
Main Authors: McDonald, Caleb B., Buffa, Laura, Bar-Mag, Tomer, Salah, Zaidoun, Bhat, Vikas, Mikles, David C., Deegan, Brian J., Seldeen, Kenneth L., Malhotra, Arun, Sudol, Marius, Aqeilan, Rami I., Nawaz, Zafar, Farooq, Amjad
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412936/
https://ncbi.nlm.nih.gov/pubmed/22634283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.05.015
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