Загрузка...

Synthesis and biological evaluation of salicylate-based compounds as a novel class of methionine aminopeptidase inhibitors

A series of salicylate-based compounds were designed and synthesized based on the simple function group replacement from our previously reported catechol-containing inhibitors of methionine aminopeptidase (MetAP). Some of these salicylate derivatives showed similar potency and metalloform selectivit...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Wang, Wen-Long, Chai, Sergio C., Ye, Qi-Zhuang
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210323/
https://ncbi.nlm.nih.gov/pubmed/22001086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.09.080
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!