Sorafenib enhances pemetrexed cytotoxicity through an autophagy- dependent mechanism in cancer cells

Pemetrexed (ALIMTA) is a folate anti-metabolite that has been approved for the treatment of non-small cell lung cancer, and has been shown to stimulate autophagy. In the present study, we sought to further understand the role of autophagy in the response to pemetrexed and to test if combination ther...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bareford, M Danielle, Hamed, Hossein A, Tang, Yong, Cruickshanks, Nichola, Burow, Matthew E, Fisher, Paul B, Moran, Richard G, Nephew, Kenneth P, Grant, Steven, Dent, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2011
Pynciau:
Autophagic Punctum
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210312/
https://ncbi.nlm.nih.gov/pubmed/21814046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.10.17029
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