Llwytho...
Obatoclax and Lapatinib Interact to Induce Toxic Autophagy through NOXA
Prior studies demonstrated that resistance to the ERBB1/2 inhibitor lapatinib could be overcome by the B cell CLL/lymphoma-2 (BCL-2) family antagonist obatoclax (GX15-070). Coadministration of lapatinib with obatoclax caused synergistic cell killing by eliciting autophagic cell death that was depend...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3310419/ https://ncbi.nlm.nih.gov/pubmed/22219388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.076851 |
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