Sorafenib enhances pemetrexed cytotoxicity through an autophagy -dependent mechanism in cancer cells

Pemetrexed (ALIMTA) is a folate anti-metabolite that has been approved for the treatment of non-small cell lung cancer, and has been shown to stimulate autophagy. In the present study, we sought to further understand the role of autophagy in the response to pemetrexed and to test if combination ther...

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書誌詳細
主要な著者: Bareford, M. Danielle, Park, Margaret A., Yacoub, Adly, Hamed, Hossein A., Tang, Yong, Cruickshanks, Nichola, Eulitt, Patrick, Hubbard, Nisan, Tye, Gary, Burow, Matthew E., Fisher, Paul B., Moran, Richard G., Nephew, Kenneth P., Grant, Steven, Dent, Paul
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139015/
https://ncbi.nlm.nih.gov/pubmed/21622715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0898
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