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PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway
Autophagy is a highly conserved, closely regulated homeostatic cellular activity that allows for the bulk degradation of long-lived proteins and cytoplasmic organelles. Its roles in cancer initiation and progression and in determining the response of tumor cells to anticancer therapy are complicated...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210306/ https://ncbi.nlm.nih.gov/pubmed/21673516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.10.16636 |
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