Moxidectin induces Cytostatic Autophagic Cell Death of Glioma Cells through inhibiting the AKT/mTOR Signalling Pathway

Moxidectin (MOX), a broad-spectrum antiparasitic drug, has been characterized as a potential anti-glioma agent. The main objective of this study was to explore autophagy induced by MOX in glioma U251 and C6 cells, and the deep underlying molecular mechanisms. In addition, the effects of autophagy on...

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Bibliografiske detaljer
Udgivet i:J Cancer
Main Authors: Liu, Jingjing, Liang, Hongsheng, Khilji, Saadia, Li, Haitao, Song, Dandan, Chen, Chen, Wang, Xiaoxing, Zhang, Yiwei, Zhao, Ning, Li, Xina, Gao, Aili
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477456/
https://ncbi.nlm.nih.gov/pubmed/32913473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.46697
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