Moxidectin induces Cytostatic Autophagic Cell Death of Glioma Cells through inhibiting the AKT/mTOR Signalling Pathway

Moxidectin (MOX), a broad-spectrum antiparasitic drug, has been characterized as a potential anti-glioma agent. The main objective of this study was to explore autophagy induced by MOX in glioma U251 and C6 cells, and the deep underlying molecular mechanisms. In addition, the effects of autophagy on...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Liu, Jingjing, Liang, Hongsheng, Khilji, Saadia, Li, Haitao, Song, Dandan, Chen, Chen, Wang, Xiaoxing, Zhang, Yiwei, Zhao, Ning, Li, Xina, Gao, Aili
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477456/
https://ncbi.nlm.nih.gov/pubmed/32913473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.46697
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