Ivermectin induces autophagy-mediated cell death through the AKT/mTOR signaling pathway in glioma cells

Glioma is one of the most common types of primary brain tumors. Ivermectin (IVM), a broad-spectrum antiparasitic drug, has been identified as a novel anticancer agent due to its inhibitory effects on the proliferation of glioma cells in vitro and in vivo. However, the ability of IVM to induce autoph...

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Detalles Bibliográficos
Publicado en:Biosci Rep
Autores principales: Liu, Jingjing, Liang, Hongsheng, Chen, Chen, Wang, Xiaoxing, Qu, Faling, Wang, Haiyang, Yang, Kongbin, Wang, Qing, Zhao, Ning, Meng, Jing, Gao, Aili
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2019
Materias:
Cancer
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900471/
https://ncbi.nlm.nih.gov/pubmed/31755894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20192489
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