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PML‐RARα interferes with erythropoiesis by repressing LMO2 in acute promyelocytic leukaemia
The PML‐RARα fusion gene, generated by the t(15;17) chromosome translocation, is regarded as the initiating factor of acute promyelocytic leukaemia (APL). In addition to the well‐known effects on blocking myeloid differentiation at the promyelocytic stage, promyelocytic leukaemia‐retinoic acid recep...
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| Publicado no: | J Cell Mol Med |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237603/ https://ncbi.nlm.nih.gov/pubmed/30320491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13917 |
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