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A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafish

Human liver cancer is one of the deadliest cancers worldwide, with hepatocellular carcinoma (HCC) being the most common type. Aberrant Ras signaling has been implicated in the development and progression of human HCC, but a complete understanding of the molecular mechanisms of this protein in hepato...

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Hlavní autoři: Nguyen, Anh Tuan, Emelyanov, Alexander, Koh, Chor Hui Vivien, Spitsbergen, Jan M., Lam, Siew Hong, Mathavan, Sinnakaruppan, Parinov, Serguei, Gong, Zhiyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Limited 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209649/
https://ncbi.nlm.nih.gov/pubmed/21729876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.007831
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