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Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish

We have previously demonstrated the pro-tumoral role of neutrophils using a kras-induced zebrafish hepatocarcinogenesis model. To further illustrate the molecular basis of the pro-tumoral role, Tumor-associated neutrophils (TANs) were isolated by fluorescence-activated cell sorting (FACS) and transc...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Huo, Xiaojing, Li, Hankun, Li, Zhen, Yan, Chuan, Agrawal, Ira, Mathavan, Sinnakaruppan, Liu, Jianjun, Gong, Zhiyuan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365535/
https://ncbi.nlm.nih.gov/pubmed/30728369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36605-8
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