A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafish

Human liver cancer is one of the deadliest cancers worldwide, with hepatocellular carcinoma (HCC) being the most common type. Aberrant Ras signaling has been implicated in the development and progression of human HCC, but a complete understanding of the molecular mechanisms of this protein in hepato...

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Bibliografiska uppgifter
Huvudupphovsmän: Nguyen, Anh Tuan, Emelyanov, Alexander, Koh, Chor Hui Vivien, Spitsbergen, Jan M., Lam, Siew Hong, Mathavan, Sinnakaruppan, Parinov, Serguei, Gong, Zhiyuan
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists Limited 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209649/
https://ncbi.nlm.nih.gov/pubmed/21729876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.007831
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