Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase

The eukaryotic replicative DNA helicase, CMG, unwinds DNA by an unknown mechanism. In some models, CMG encircles and translocates along one strand of DNA while excluding the other strand. In others, CMG encircles and translocates along duplex DNA. To distinguish between these models, replisomes were...

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Auteurs principaux: Fu, Yu V., Yardimci, Hasan, Long, David T., Ho, The Vinh, Guainazzi, Angelo, Bermudez, Vladimir P., Hurwitz, Jerard, van Oijen, Antoine, Schärer, Orlando D., Walter, Johannes C.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209622/
https://ncbi.nlm.nih.gov/pubmed/21925316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.045
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