Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase

The eukaryotic replicative DNA helicase, CMG, unwinds DNA by an unknown mechanism. In some models, CMG encircles and translocates along one strand of DNA while excluding the other strand. In others, CMG encircles and translocates along duplex DNA. To distinguish between these models, replisomes were...

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Hlavní autoři: Fu, Yu V., Yardimci, Hasan, Long, David T., Ho, The Vinh, Guainazzi, Angelo, Bermudez, Vladimir P., Hurwitz, Jerard, van Oijen, Antoine, Schärer, Orlando D., Walter, Johannes C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209622/
https://ncbi.nlm.nih.gov/pubmed/21925316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.045
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