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TRIM5α Does Not Affect Simian Immunodeficiency Virus SIV(mac251) Replication in Vaccinated or Unvaccinated Indian Rhesus Macaques following Intrarectal Challenge Exposure
TRIM5α is a natural resistance factor that binds retroviral capsid proteins and restricts virus replication. The B30.2/SPRY domain of TRIM5α is polymorphic in rhesus macaques, and some alleles are associated with reduced simian immunodeficiency virus (SIV) SIV(mac251) and SIV(smE543) replication in...
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| Glavni autori: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209340/ https://ncbi.nlm.nih.gov/pubmed/21917950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05707-11 |
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