TRIM5α Does Not Affect Simian Immunodeficiency Virus SIV(mac251) Replication in Vaccinated or Unvaccinated Indian Rhesus Macaques following Intrarectal Challenge Exposure

TRIM5α is a natural resistance factor that binds retroviral capsid proteins and restricts virus replication. The B30.2/SPRY domain of TRIM5α is polymorphic in rhesus macaques, and some alleles are associated with reduced simian immunodeficiency virus (SIV) SIV(mac251) and SIV(smE543) replication in...

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Detalhes bibliográficos
Main Authors: Fenizia, Claudio, Keele, Brandon F., Nichols, David, Cornara, Stefano, Binello, Nicolò, Vaccari, Monica, Pegu, Poonam, Robert-Guroff, Marjorie, Ma, Zhong-Min, Miller, Christopher J., Venzon, David, Hirsch, Vanessa, Franchini, Genoveffa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209340/
https://ncbi.nlm.nih.gov/pubmed/21917950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05707-11
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